The restaurant, which opened beneath Capital Radio in 2015 following a multi-million pound investment, closed earlier this month.
It was originally expected to remain open as one of 51 sites to be saved following a takeover of the company by Breal Capital and Calveton UK last October.
The closure means that the brand, which at one point had more than 100 UK sites but which now operates just 50, no longer has a presence in central London, although it does have sites in the capital at Westfield Stratford City, The O2, and Wembley Park.
TGI Friday is one of a number of high-profile restaurants to leave the popular tourist destination in the past few years. Last year Black & White Hospitality closed its flagship Mr White’s restaurant at Leicester Square after just two years’ trading. The huge, 14,500sq ft venue was set over a number of floors and had a 600-seat capacity.
TGI Fridays’ UK franchise was bought by Breal Capital and Calveton in a deal that saved at least 51 of the American bar and restaurant brand’s sites, with a further 36 restaurants closing.
The deal came after TGI’s previous owner Hostmore filed for administration having abandoned an all-share acquisition of TGI Fridays’ US business.
A recent report by CGA by NIQ and AlixPartners found that restaurant closures accelerated in the final quarter of 2024 due to mounting cost pressures and changing consumer habits, with an average of just over eight net closures per day between October and December.