Currently trading day time only, the Nile Street venue will offer dinner from Thursday to Saturday from 5 April.
Lost in the Lanes was launched in 2018 by former speech therapist Natalie Demetriou.
The kitchen is now headed by human rights lawyer turned chef Sophie Taverner, who has a CV that includes Ibiza Food Studio and La Finca in Spain and London’s Lyle’s.
Her evening menu will include potato rosti with ox cheek ragu, Parmesan, chives; cavatelli with kale pesto; and whole roast plaice with lime and chilli butter.
Desserts will include pavlova with creme Anglaise, Chantilly cream and rhubarb; and chocolate pannacotta with oat crumble.
Lost in the Lanes is billed as a chef-led restaurant where everyone feels welcome offering responsibly sourced, paired-back, ingredient-led dishes.